Polynucleotides (PDRN) — Evolve Aesthetics Clinic, Fakenham Norfolk

Polynucleotides

Regenerate. Renew. Reveal.

An advanced regenerative treatment that stimulates cellular repair and renewal — for progressively improved skin quality, tone and texture.

Treatment time

45 minutes

Downtime

Minimal. Mild redness or small bumps at injection sites may occur, resolving within a few hours.

Longevity

Results are progressive and cumulative. Maintenance treatments are recommended every 3–6 months after the initial course.

What is it?

About Polynucleotides (PDRN)

Polynucleotides (also known as PDRN — Polydeoxyribonucleotide) are an advanced injectable treatment derived from highly purified salmon DNA. They work by stimulating cellular repair and regeneration, improving skin quality, tone and texture from within. Unlike hyaluronic acid treatments, polynucleotides work by triggering the skin's own repair mechanisms rather than adding a substance to the skin.

Suitable for

Is this right for me?

Polynucleotides are suitable for adults seeking skin regeneration, improved skin tone and texture, or treatment of under-eye concerns such as dark circles and hollowing. They are particularly effective for skin that has been damaged by sun exposure, ageing or environmental factors.

Benefits

What to expect

Stimulates cellular repair and skin regeneration

Improves skin tone, texture and elasticity

Effective for under-eye dark circles and hollowing

Anti-inflammatory properties

Progressive results that improve over a course of treatment

Results

What results can I expect?

Results develop progressively over a course of 3 sessions. Improvement in skin quality, tone and texture becomes visible over 4–8 weeks.

FAQs

Frequently asked questions

Is PDRN safe?

Yes. Polynucleotides have an excellent safety profile and have been used in medical and aesthetic practice for many years. They are highly purified and well-tolerated.

How many sessions are needed?

A course of 3 sessions is recommended, spaced 2–4 weeks apart. Results are progressive and cumulative, improving with each session.

Can polynucleotides treat under-eye concerns?

Yes — polynucleotides are particularly effective in the under-eye area, where they can improve dark circles, skin quality and mild hollowing. This is a delicate area that requires specialist expertise.

Can polynucleotides be combined with other treatments?

Yes — polynucleotides combine well with skin boosters, anti-wrinkle injections and other aesthetic treatments. A combined approach is often recommended for optimal results.

Pricing

How much does it cost?

Pricing is discussed at your consultation and tailored to your individual treatment plan.